Journal: Heliyon
Article Title: Live virus neutralizing antibodies against pre and post Omicron strains in food and retail workers in Québec, Canada
doi: 10.1016/j.heliyon.2024.e31026
Figure Lengend Snippet: Neutralizing antibody titers against ancestral SARS-CoV-2, Delta, BA.1, BA.2, BA.2.12.1, BA.4 and BA.5 strains in all volunteers regarding the number of vaccine doses received and if they were infected before or after vaccinations. (A) Group 1 (n = 16); infected, Pfizer (n = 11), Moderna (n = 3), Pfizer/Moderna (n = 1) or AstraZeneca (n = 1)); Groupe 2 (n = 144); 2 doses of Pfizer (n = 85), Pfizer/Moderna or vice versa (n = 2), Moderna/Moderna (n = 41) and AstraZeneca and Pfizer or Moderna (n = 16); Group 3 (n = 84); 3 doses of Pfizer (n = 17), 3 doses of Moderna (n = 16), Moderna/Moderna/Pfizer (n = 5), Pfizer/Pfizer/Moderna (n = 19), Pfizer/Moderna/Pfizer or Moderna (n = 3), AstraZeneca/AstraZeneca/Pfizer or Moderna (n = 4) or AstraZeneca/Pfizer or Moderna/Moderna (n = 20); Group 4 (n = 36): participants received at least 2 doses of vaccine (Pfizer/Pfizer (n = 25), Moderna/Moderna (n = 7), AstraZeneca/AstraZeneca or AstraZeneca/Moderna (n = 4)) and then were infected. (B) Neutralizing antibody titers for each participant against ancestral SARS-CoV-2, Delta, BA.1, BA.2, BA.2.12.1, BA.4 and BA.5 strains regarding type of vaccine regimen. Each circle represents a single participant. In the first group, the green and red points represent participants vaccinated with 1 and 3 doses and then infected, respectively. Bars identify mean NtAbs titers of the group with 95 % CI. The horizontal dashed line indicates the limit of detection for the neutralization assay (neutralizing titer of 10). The samples that did not neutralize SARS-CoV-2 at 1:20 serum dilution was given a neutralizing titer of 10 for graphic representation and statistical analysis. The fold-change of the mean NtAbs titer and significant p-value ( p ≤ 0.05) are denoted on the line. Significance was assessed with Kruskal-Wallis one-way ANOVA followed by Dunn's multiple comparison test.
Article Snippet: Mix AstraZeneca/Pfizer or Moderna , – , , – , , 49 , (24).
Techniques: Infection, Neutralization, Comparison